References and Scientific Studies for Ingredients
GOTU KOLA
Centella asiatica (Gotu kola) as a neuroprotectant and its potential role in healthy ageing - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S092422441730558
Frontiers | Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review (frontiersin.org)
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2020.568032/full
View of 01. Clinical and therapeutic benefits of Centella asiatica (thepab.org)
https://www.thepab.org/index.php/journal/article/view/2004/1239
4798 (pinellinutraceuticals.com)
https://pinellinutraceuticals.com/wp-content/uploads/2023/01/FUNCTIONAL-PROPERTIES-OF-CENTELLA-ASIATICA-L.-A-REVIEW.pdf
ROSE HIP
An overview of therapeutic potentials of Rosa canina- a traditionally valuable herb (wcrj.net)
https://www.wcrj.net/wp-content/uploads/sites/5/2020/11/e1580.pdf
In vivo anti-inflammatory and antinociceptive activity of the crude extract and fractions from Rosa canina L. fruits - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0378874107001638
DEVILS CLAW
Anti-inflammatory activity of Devil’s claw in vitro systems and their active constituents - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0308814610010599
Molecules | Free Full-Text | The Fight against Infection and Pain: Devil’s Claw (Harpagophytum procumbens) a Rich Source of Anti-Inflammatory Activity: 2011–2022 (mdpi.com)
https://www.mdpi.com/1420-3049/27/11/3637
DIPSACI ROOT
Systems pharmacology dissection of action mechanisms of Dipsaci Radix for osteoporosis - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0024320519307477
HORSETAIL STEM
Pharmaceuticals | Free Full-Text | Horsetail (Equisetum hyemale) Extract Accelerates Wound Healing in Diabetic Rats by Modulating IL-10 and MCP-1 Release and Collagen Synthesis (mdpi.com)
https://www.mdpi.com/1424-8247/16/4/514#
LION’S MANE MUSHROOM
Neuroregenerative Potential of Lion's Mane Mushroom, <i>Hericium erinaceus</i> (Bull.: Fr.) Pers. (Higher Basidiomycetes), in the Treatment of Peripheral Nerve Injury (Review) - International Journal of Medicinal Mushrooms, Volume 14, 2012, Issue 5 - Begell House Digital Library
https://www.dl.begellhouse.com/journals/708ae68d64b17c52,03ea8c440cfbb276,23c2fd3840f4e0c9.html#
Activity of Aqueous Extracts of Lion's Mane Mushroom <i>Hericium erinaceus</i> (Bull.: Fr.) Pers. (Aphyllophoromycetideae) on the Neural Cell Line NG108-15 - International Journal of Medicinal Mushrooms, Volume 9, 2007, Issue 1 - Begell House Digital Library
https://www.dl.begellhouse.com/journals/708ae68d64b17c52,0d49dda96a2a7147,6ce1a4f7295df1fb.html
MSM
Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S1063458405002852
Methylsulfonylmethane for treatment of low back pain: A safety analysis of a randomized, controlled trial - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0965229919306417
GLYCINE
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis | Amino Acids (springer.com)
https://link.springer.com/article/10.1007/s00726-018-2611-x
A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis | Journal of Biosciences (springer.com)
https://link.springer.com/article/10.1007/s12038-009-0100-9
THIAMINE - VITAMIN B1
A Review of the Biochemistry, Metabolism and Clinical Benefits of Thiamin(e) and Its Derivatives (wiley.com)
https://onlinelibrary.wiley.com/doi/epdf/10.1093/ecam/nek009
